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Hepatitis is an inflammatory liver disease that is spread by blood and body fluids such as sex, needle sharing, blood transfusion, tattoos. Hep B causes clinical manifestations such as yellowish discoloration of your eyes, specifically your sclerae. Other symptoms include fever and bodily complaints, such as weakness and anorexia (no desire to eat). When you experience yellowish discoloration of your sclerae, you need to undergo some laboratory tests to exactly find out your medical problem.
Is it hepatitis B, A, or something else? There could be an obstruction in your hepato-biliary tree, which is the tube connecting your liver to your gallbladder and to your intestine. However, if there was a recent history that you had a blood transfusion, intravenous injections, or tattoo construction in any part of your skin, it is possible that you have been afflicted with hepatitis B.
The disease itself could be well managed by medical doctors in the hospital or in medical clinics in your locality. However, what is alarming and life-threatening is the fact that hepatitis B could lead to liver cancer. It means that if you have been afflicted with hepatitis B, many years later, you will suffer from liver cancer.
The correlation coefficient between hepatitis B and liver cancer is almost 100%. Thus, if you have been afflicted with the disease at a certain time in your life, you will surely have liver cancer in the future. Remember that liver cancer is largely and generally fatal. Thus, you need to prevent its occurrence by having the vaccination for hepatitis B.
Generic and brand names
The generic name of the vaccine is Hepatitis B (rDNA) vaccine (adsorbed). The brand name is Engerix-B or Euvax B.
Composition of the vaccine
The vaccine is composed of spherical particles of 20 nm in average diameter containing non-glycosylated hepatitis B surface antigen (HBsAg) polypeptides and a lipid matrix consisting mainly of phospholipids.
Mechanism of action
If the HBsAg is injected into your system, your body will produce antibodies against hepatitis B, thereby protecting you from contracting the disease.
Schedule of administration
The first dose of the vaccine is given at elected date, followed by 2nd dose after 1 month from the first dose. The 3rd dose is given five months after the 2nd dose. There is also a rapid series able to be given 0,7,21 days and then 1 year.
Indications and usage
This vaccine is indicated for active immunization against hepatitis B infection for all subjects of all ages considered at risk of exposure to the disease. The following groups are identified to be at high and increased risk of the infection, thereby necessitating the administration of the hepatitis B vaccine:
Vaccination should be postponed if the subject suffers from an acute severe febrile illness. Minor infection, however, is not a contraindication for immunization.
Dosage and mode of administration
The dose per injection is 20 ug (1.0 ml) for 20 years old and older adults, to be given intramuscularly. This vaccine should never be injected intravenously, subcutaneously, or intradermally.